<p><em>EGFR</em> mutations are significantly associated with visceral pleural invasion development in non-small-cell lung cancer patients</p>
نویسندگان
چکیده
منابع مشابه
Influence of visceral pleural invasion on survival in completely resected non-small-cell lung cancer.
OBJECTIVES Although the prognostic implications of visceral pleural invasion (VPI) are well established, it remains controversial whether the extent of VPI affects survival in patients with completely resected non-small-cell lung cancer (NSCLC). In addition, the impact of VPI according to nodal status is unclear. We evaluated the influence of the extent of pleural invasion on survival by analys...
متن کاملEffect of visceral pleural invasion on the prognosis of patients with lymph node negative non‐small cell lung cancer
BACKGROUND Visceral pleural invasion (VPI) is an adverse prognostic factor in non-small cell lung cancer (NSCLC); however, its effect in relation to tumor size remains under debate. To better understand the prognostic impact and potential consequences for staging, we examined correlations between VPI and clinicopathologic characteristics in patients with NSCLC, particularly those with lymph nod...
متن کاملClinical impact of visceral pleural, lymphovascular and perineural invasion in completely resected non-small cell lung cancer.
OBJECTIVES This study is conducted to show the relationship between visceral pleural, lymphovascular, and perineural invasion, and other clinicopathologic characteristics and their significance as prognostic factors. METHODS The clinicopathologic characteristics of 289 patients who underwent a potentially curative surgical resection between 2000 and 2009 in our clinic were reviewed retrospect...
متن کاملMutations in Non-Small Cell Lung Cancer
Epidemiological studies have demonstrated a strong association between tobacco use and lung cancer; however, the genetic targets of these carcinogens and the role of other environmental agents in this process have yet to be defined. We examined the contribution of alcohol use and cigarette smoking to p53 gene mutations in patients with non-small cell lung cancer. Mutations of the p53 gene were ...
متن کاملExtent of visceral pleural invasion and the prognosis of surgically resected node‐negative non‐small cell lung cancer
BACKGROUND Visceral pleural invasion (VPI) is generally considered a poor prognostic factor in non-small cell lung cancer (NSCLC). VPI is defined as penetration beyond the elastic layer of visceral pleura (PL1), including the visceral pleural surface without the involvement of adjacent structures (PL2) by cancer cells. The aim of this study was to evaluate the influence of the extent of VPI on ...
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ژورنال
عنوان ژورنال: Cancer Management and Research
سال: 2019
ISSN: 1179-1322
DOI: 10.2147/cmar.s195747